Tag Archives: CRISPR

Roundtables: CRISPR Babies—Six years later

CRISPR Babies: Six years later Speakers: He Jiankui, CRISPR Pioneer, Antonio Regalado, senior editor for biomedicine, and Mat Honan, editor in chief Gene editing can correct or improve the DNA of human embryos, essentially opening the door to “technological evolution” of our species. But in 2018, a premature attempt to use gene editing led to […]

Gene editing had a banner year in 2023

Gene editing had a banner year in 2023

It really shouldn’t have come as a surprise. Perhaps no technology has more power to transform medicine, and its vast potential is just beginning to be realized. Gene editing can be used to delete, insert, or alter portions of our genetic code. We’ve been able to modify DNA for years, but newer technologies like CRISPR […]

The lucky break behind the first CRISPR treatment

The lucky break behind the first CRISPR treatment

The association technique hasn’t always paid off—but starting in 2007, the gene searches hit pay dirt for sickle-cell. In one study, for instance, a team in Italy studied DNA from thousands of Sardinians (some of whom had beta-thalassemia, another hemoglobin disorder, which is shockingly common on the island) as well from Americans with sickle-cell. When […]

Three people were gene-edited in an effort to cure their HIV. The result is unknown.

Three people were gene-edited in an effort to cure their HIV. The result is unknown.

Vaccine makers have also struggled because HIV kills the very immune cells meant to stop infection. But a decade ago, Khalili says, he realized that CRISPR might offer a way to cure the infection without involving the immune system: by deleting the virus’s genes from their hiding places. “If the viral gene is in your […]

Forget designer babies. Here’s how CRISPR is really changing lives

Forget designer babies. Here’s how CRISPR is really changing lives

Even then, patients won’t get the treatments if insurers and governments balk at paying. It’s a real risk. For instance, a different gene therapy for beta-thalassemia, developed by Bluebird Bio, was pulled out of the European market after governments there refused to pay the $1.8 million price.   CRISPR 2.0 The first generation of CRISPR treatments […]

A de-extinction company is trying to resurrect the dodo

A de-extinction company is trying to resurrect the dodo

Even if Colossal can make what it terms “a functional proxy for the dodo,” there won’t be a clear answer about where to put it. The big agricultural industry in Mauritius is sugarcane farming, and there are plenty of rats and other non-native predators around. “It would not really be a dodo—it would be a […]

The creators of a new large language model called BLOOM want to democratize AI

The creators of a new large language model called BLOOM want to democratize AI

The news: A volunteer in New Zealand has become the first person to undergo DNA editing in order to lower their blood cholesterol, a step that may foreshadow wide use of the technology to prevent heart attacks. How did they do it?: The experiment involved injecting a version of the gene-editing tool CRISPR in order […]

An albino opossum proves CRISPR works for marsupials, too

While kangaroos and koalas are more well-known, researchers who study marsupials often use opossums in lab experiments, since they’re smaller and easier to care for. Gray short-tailed opossums, the species used in the study, are related to the white-faced North American opossums, but they’re smaller and don’t have a pouch. The researchers at Riken used […]