Tag Archives: sickle cell

Vertex developed a CRISPR cure. Now it wants a pill to treat sickle-cell disease.

Vertex developed a CRISPR cure. Now it wants a pill to treat sickle-cell disease.

Such drawbacks are why a pill to alleviate sickle-cell, if developed, could sweep CRISPR from the playing field. A pill version could also resolve a brewing moral dilemma: Vertex so far has no plans to offer its gene-editing treatment in those countries where sickle-cell is most common. A wide ribbon of lower-income nations across the […]

The lucky break behind the first CRISPR treatment

The lucky break behind the first CRISPR treatment

The association technique hasn’t always paid off—but starting in 2007, the gene searches hit pay dirt for sickle-cell. In one study, for instance, a team in Italy studied DNA from thousands of Sardinians (some of whom had beta-thalassemia, another hemoglobin disorder, which is shockingly common on the island) as well from Americans with sickle-cell. When […]

Forget designer babies. Here’s how CRISPR is really changing lives

Forget designer babies. Here’s how CRISPR is really changing lives

Even then, patients won’t get the treatments if insurers and governments balk at paying. It’s a real risk. For instance, a different gene therapy for beta-thalassemia, developed by Bluebird Bio, was pulled out of the European market after governments there refused to pay the $1.8 million price.   CRISPR 2.0 The first generation of CRISPR treatments […]